Basic knowledge of traditional Chinese medicine bai shao
[Medicinal name] Bai Shao (white peony root), Hang Bai Shao (Hangzhou white peony root), Sheng Bai Shao (raw white peony root), Chao Bai Shao (fried white peony root), Da Bai Shao (big white peony root).
[Properties] Slightly cold in nature; bitter, sour, sweet; returns to liver and spleen channels.
[Efficacy] Pinggan relieves pain, nourishes blood and regulates menstruation, restrains yin and stops sweating. For headache and dizziness, hypochondriac pain, abdominal pain, spasm and pain in limbs, blood deficiency and chlorosis, irregular menstruation, spontaneous sweating, night sweating.
[Taboo] It should not be used together with veratrum. Deficiency and cold syndrome should not be used alone.
The traditional Chinese medicine bai shao is the root of the perennial herb Paeoniae officinalis of Ranunculaceae. Cultivated in Anhui (Bo Bai Shao), Zhejiang (Hang Bai Shao), Hunan, Sichuan (Chuan Bai Shao) and other places. Excavated in summer and autumn, removed the soil and roots, peeled, soaked in boiling water or slightly boiled until evenly heated, and dried in the sun. Moisten slices when serving. For raw use, frying or wine frying.
The efficacy of the traditional Chinese medicine bai shao
[Medicinal Efficacy] Soothing the liver and regulating qi, softening the liver and nourishing blood, relieving pain in the middle, calming the liver and restraining yin.
1. Enrich blood. For the treatment of:
(1) Blood deficiency, irregular menstruation, dysmenorrhea, metrorrhagia, accompanied by dizziness, fatigue, palpitation and insomnia.
(2) Deficiency of blood and lack of nourishment of the liver vessels, limb spasms, joint stiffness, and difficulty in flexion and extension.
2. Reinforce the yin and soften the liver. For the treatment of:
(1) Consumption of yin fluid in the late stage of febrile disease, Cramps of hands and feet, slanted mouth, crooked eyes, dry mouth without thirst, weak pulse and crimson tongue.
(2) Deficiency of liver yin, hyperactivity of liver yang, dizziness, tinnitus, numbness of limbs.
3. Pain relief. For the treatment of:
(1) Pain in the abdomen, chest and hypochondriac, such as deficiency and cold in the middle Jiao, abdominal pain.
(2) Discomfort of liver qi, hypochondriac pain.
(3) Deficiency of yin and blood, twitching pain in the calf.
4. In addition, white peony can also treat:
(1) Dysentery, diarrhea. Dysentery, abdominal pain, tenesmus.
(2) Spontaneous sweating, night sweating.

Applicable people and contraindicated people of traditional Chinese medicine bai shao
Applicable people:
People with blood deficiency and yin deficiency, pain in the chest, abdomen, hypochondriac, pain in the liver area, and pain in cholecystitis and gallstones should eat it;
Dysentery, abdominal pain, women who have abdominal pain during menstruation should eat;
Spontaneous sweating, easy sweating and night sweating should be eaten;
Gastrocnemius muscle spasm, limb spasm and pain, patients with restless legs syndrome should eat;
Cooperating with licorice can relieve various pains in the chest, abdomen and limbs.
Contraindicated people:
Paeoniae Alba is cold in nature, and those with abdominal pain and diarrhea due to deficiency and cold should not eat it;
Do not eat when children have measles;
Those who take the traditional Chinese medicine veratrum should not eat it.
Remarks: Paeoniae Alba is an important compatible drug in many famous prescriptions:
Guizhi Decoction that harmonizes Yingwei, relieves exterior and reduces fever;
Siwu Decoction for nourishing blood and regulating menstruation;
Sini powder and Xiaoyao powder for soothing the liver and stomach;
Recipe for Harmonizing the Liver and Spleen;
Da Bupleurum Decoction for clearing liver and purging fire;
Guizhi Shaoyao Zhimu Decoction for treating Lijie arthralgia and so on.

The role of the traditional Chinese medicine bai shao
(1) Regulating immunity:
Enhancing the phagocytosis of macrophages and white blood cells: Baishao water decoction and total glucosides of paeony can significantly improve the phagocytosis of peritoneal macrophages in mice.
Both paeonifloric acid polysaccharide and neutral polysaccharide can activate the function of reticuloendothelial system.
Regulation of T lymphocyte function: total glucosides of paeony have a two-way regulation effect on T cell function. Promotes induction of specific and nonspecific regulatory cells. Intraperitoneal injection of total glucosides of paeony can significantly promote specific Ts cells, and can antagonize the immunosuppressive effect of cyclophosphamide.
Regulating humoral immune function: intraperitoneal injection of total paeoniflorin had no significant effect on SRRC hemolysin antibody in normal mice, but it could antagonize the immunosuppression caused by cyclophosphamide and restore the immune function to normal levels. It can also significantly reduce the atrophy of thymus and spleen and the inhibition of hemolysin antibody production caused by 60CO irradiation. Total glucosides of paeony can not only promote the production of IgM, but also reduce the production of IgM, and play a two-way regulation effect on humoral immunity.
(2) Anti-inflammatory:
Paeoniflorin has a significant anti-inflammatory effect, and paeonol has a strong anti-inflammatory effect. Paeoniflorin and paeonol have significant inhibitory effects on capillary hyperpermeability, exudation, edema, and immune inflammation caused by various inflammatory agents.
(3) For the digestive system
Liver protection: Paeoniae Alba has significant protection against various experimental liver injuries. Paeoniae Alba can significantly reduce A1T for acute liver injury and restore liver cell lesions and necrosis.
For mice with autoimmune hepatitis, intraperitoneal injection of total paeoniflorin can significantly reduce ALT, restore normal liver cell ultrastructure, active liver cell regeneration, and significantly reduce the degree of liver lesions. The proliferative response of splenic lymphocytes induced by liver Soviet membrane-specific lipoprotein was restored, indicating that total paeoniflorin not only has a significant therapeutic effect on autoimmune hepatitis, but also has a function-dependent immune regulation effect.
Antispasmodic: Radix Paeoniae Alba and Paeoniflorin have significant antispasmodic effect on intestinal smooth muscle. Shaoyao Gancao decoction can promote gastric peristalsis and increase contraction force at low concentration, and inhibit contraction at high concentration. Shaoyao Gancao decoction, peony and licorice can all inhibit the contraction of the ileum caused by parasympathetic nerve excitation. Peony can inhibit the release of acetylcholine in parasympathetic nerve endings, which is presynaptic inhibition. Paeoniflorin is the main component of antispasmodic, and antispasmodic of peony is also related to other components.
The inhibitory effect of Shaoyao Gancao Decoction on rabbit intestinal smooth muscle was stronger than that of the two herbs in the prescription alone.
The peony in Shaoyao Gancao Decoction is selected from 5 kinds of processing methods of peony, all of which have significant inhibitory effect on intestinal spasm caused by acetylcholine. As the dose increases, the effect also increases. Among the 5 processing methods, the effect of stir-frying white peony root with vinegar is the strongest, followed by bran-frying, wine-frying, and clear-frying is the weakest.
Anti-gastric ulcer: paeoniflorin and paeonol can significantly inhibit stress ulcer and gastric acid secretion in mice. Paeoniae officinalis and licorice have a synergistic effect on gastric acid secretion.

(4) Cardiovascular
The aqueous extract of Radix Paeoniae Alba can significantly prolong the survival time of mice with myocardial hypoxia induced by isoproterenol, antagonize myocardial ischemia induced by vasopressin, and increase myocardial nutritional blood flow.
Intravenous injection of total paeoniflorin can increase systolic and diastolic blood pressure in rabbits and cats.
The aqueous extract of Paeoniae Alba can inhibit ADP-induced platelet aggregation, and total glucosides of paeoniflorin can reduce the wet weight of platelet thrombus and inhibit thrombus formation. Its active ingredients are oxypaeoniflorin, benzoylpaeoniflorin, and benzoyloxypaeoniflorin.
(5) Analgesia, sedation, anticonvulsion, cooling:
Analgesic: Peony, Paeoniflorin and Shaoyao Gancao Decoction all have significant analgesic effects. Paeoniflorin has a synergistic effect with morphine and clonidine.
Sedation: Both paeoniflorin and paeonol have a sedative effect and can enhance the effect of hypnotics.
Anticonvulsant: Both paeoniflorin and paeonol have anticonvulsant effect, and can significantly reduce EEG spasm waves, suggesting that they have antiepileptic effect.
Antipyretic: Paeoniflorin can lower the body temperature of normal mice, but has no antipyretic effect on fever. The cooling effect of paeoniflorin is related to its ability to sensitize H1 receptors in the brain.
Paeonol can not only reduce the body temperature of normal mice, but also has antipyretic and cooling effects on fever.
(6) Enhance hypoxia resistance, anti-oxidation and anti-fatigue
Enhance hypoxia tolerance: intraperitoneal injection of water extract of Radix Paeoniae Alba can significantly prolong the death time of mice under normal pressure and hypoxia conditions, and can significantly prolong the hypoxia survival time of mice under decompression conditions.
Anti-oxidation: Paeoniflorin and Paeoniflorin can scavenge oxygen free radicals, and Paeoniflorin can significantly inhibit the formation of liver lipid peroxidation and the increase of AlT. It shows that the components of Radix Paeoniae Alba have antioxidant effect.
Anti-fatigue: The alcohol extract of Paeoniae Alba can significantly prolong the swimming time of mice.
(7) Others
The effect on endocrine Paeoniflorin has two-way regulating effect on the hypothalamus-pituitary-adrenal axis function, which can not only significantly increase the plasma corticosterone and ACTH of rats under stress state, but also make the plasma corticosterone under highly excited state , ACTH and β-endorphin responses decreased.
Antibacterial and antiviral: Paeoniae Alba decoction has broad-spectrum antibacterial and antiviral effects.
Anti-mutation effect: Radix Paeoniae Alba has a strong inhibitory effect on the mutation of Salmonella typhimurium.

Types of traditional Chinese medicine bai shao and their effects
Prescription name
Bai Shao (white peony root). Hang Bai Shao (Hangzhou White Peony). Da Bai Shao (Big White Peony). Sheng Bai Shao(raw white peony root). Chao Bai Shao (fried white peony root). Chao Hang Shao (fried Hangzhou white peony root). Jiu Bai Shao (Wine White Peony). Cu Bai Shao (Vinegar White Peony). Jiao Bai Shao (charred white peony root). Bai Shao Tan (white peony charcoal) and so on.
The prescription writes Bai Shao (white peony root), Hang Bai Shao (Hangzhou white peony root), and Da Bai Shao (big white peony root). Both refer to Sheng Bai Shao (raw white peony root), which removes impurities from the original medicine, moistens the slices, and is used raw as medicine.
Chao Bai Shao (fried white peony root) is also called roasted white peony root. Fry white peony slices with bran over low heat until light yellow, slightly scorched, sift out wheat bran, let cool and use as medicine.
Jiu Bai Shao (wine white peony root) is also known as wine fried white peony root and wine peony root. Sprinkle the white peony slices with rice wine and mix well, and then fry them to dry and use them as medicine. The coldness is alleviated, and the effect of promoting blood circulation is enhanced.
Cu Bai Shao (Vinegar White Peony) is also known as Vinegar Fried White Peony, Vinegar Peony. Spray white peony slices with rice vinegar, stir-fry them with a slow fire and add them into the medicine. It tends to restrain the liver to relieve pain, nourish blood to stop bleeding.
Jiao Bai Shao (charred white peony root) is also known as Jiao Shao and white peony charcoal. Stir-fry the white peony slices with strong fire until they are scorched black, save their properties, take them out and extinguish the sparks with clear water, then dry them and use them as medicine. Preferring to stop bleeding.

Bai Shao Extract Granules Supplier and Manufacturer – Tianjiang
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