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"Quality Management Standards for Production of Chinese Medicinal Materials" issued and implemented

2022-03-08 Pageviews:692 Source:Tianjiang

In order to implement the "Opinions of the Central Committee of the Communist Party of China and the State Council on Promoting the Inheritance, Innovation and Development of Traditional Chinese Medicine", promote the standardized production of traditional Chinese medicinal materials, strengthen the quality control of traditional Chinese medicinal materials, and promote the high-quality development of traditional Chinese medicine, according to the "Medicine Administration Law of the People's Republic of China" The National Medical Products Administration, the Ministry of Agriculture and Rural Affairs, the National Forestry and Grass Administration, and the State Administration of Traditional Chinese Medicine have researched and formulated the "Quality Management Specification for the Production of Chinese Medicinal Materials" (hereinafter referred to as the Specification), which are hereby promulgated and implemented, and relevant matters will be announced. as follows:

1. This standard is applicable to the whole-process management of Chinese medicinal materials production enterprises to standardize the production of traditional Chinese medicinal materials, and is the basic requirement for the standardized production and management of traditional Chinese medicinal materials. The traditional Chinese medicinal materials involved in this specification refer to medicinal plants, medicinal animals and other resources, which are used in the production of traditional Chinese medicines after standardized planting (including ecological planting, wild tending and imitation wild cultivation), breeding, harvesting and processing at the place of origin. Medicinal raw materials for decoction pieces and traditional Chinese medicine preparations.

The Chinese herbal medicine production enterprises referred to in this announcement include professional planting and breeding cooperatives or associations with an enterprise nature.

2. Encourage Chinese herbal medicine manufacturers such as Chinese herbal decoction pieces manufacturers and Chinese patent medicine marketing license holders to establish their own and jointly build Chinese herbal medicine production enterprises and production bases that comply with this standard in the production areas of Chinese herbal medicines, and extend the drug quality management system to the production areas of Chinese herbal medicines .

Encourage traditional Chinese medicine production enterprises to give priority to the use of traditional Chinese medicinal materials that meet the requirements of this specification. If there are clear requirements in the drug approval documents, etc., the traditional Chinese medicine manufacturer shall use the traditional Chinese medicinal materials that meet the requirements of this specification in accordance with the regulations. Relevant traditional Chinese medicine manufacturers shall conduct supplier audits in accordance with the law, conduct audits and inspections in accordance with the requirements of this specification, and ensure compliance with the requirements.

3. When using traditional Chinese medicinal materials that meet the requirements of this specification, relevant traditional Chinese medicine manufacturers can refer to the relevant regulations on drug label management, and mark "the medicinal materials meet the GAP requirements" in the appropriate position of the drug label, and can publicize them according to law. For traditional Chinese medicine compound preparations, all prescription ingredients must meet the requirements of this specification before they can be labeled.

Provincial-level drug supervision and administration departments shall strengthen supervision and inspection, and conduct extended inspections of corresponding Chinese herbal medicine manufacturers if necessary, focusing on whether they comply with this standard, for traditional Chinese medicine manufacturers that should use or label the use of traditional Chinese medicinal materials that comply with this specification. If it is found to be inconsistent, it shall be strictly investigated and punished according to law, and the Chinese medicine manufacturer shall be ordered to make corrections within a time limit, cancel the labeling, etc., and disclose the corresponding Chinese herbal medicine manufacturer and its varieties, and notify the people's government of the place where the Chinese herbal medicine is produced.

4. Under the leadership of the provincial party committee and the provincial government, the relevant administrative departments of each province shall cooperate and assist the people's government of the origin of Chinese medicinal materials to do a good job in the standardized development of Chinese medicinal materials, such as improving the working mechanism for the high-quality development of the Chinese medicinal materials industry; formulating the development plan of the Chinese medicinal materials industry; Promote incentive policies for the standardized development of Chinese medicinal materials; establish ledgers and credit files for Chinese medicinal materials production enterprises and their production bases, and implement dynamic supervision; establish an information platform for the standardized production and traceability of traditional Chinese medicinal materials. Provinces with a good foundation for standardized and intensive production of traditional Chinese medicinal materials are encouraged to study and formulate detailed implementation rules based on the actual development of traditional Chinese medicinal materials in their jurisdictions, actively explore and advance, and accumulate experience in the in-depth promotion of this standard.

5. Relevant administrative departments in each province shall inspect and provide technical guidance on the implementation and promotion of this Code in accordance with their duties. The agricultural and rural departments take the lead in providing guidance on the provision of Chinese herbal medicine seeds, seedlings and provenance, field management, pesticide and fertilizer use, and pest control. The forestry and grassland departments take the lead in providing guidance on the ecological planting, wild tending, and imitation wild cultivation of traditional Chinese medicinal materials, as well as the planting and breeding of traditional Chinese medicinal materials that fall under the category of endangered management. The traditional Chinese medicine management department shall coordinately provide guidance on seedlings, standardized planting, harvesting and processing, and ecological planting of traditional Chinese medicinal materials. The drug supervision and management department shall carry out extended inspections on corresponding Chinese herbal medicine production enterprises, and provide guidance on medicinal requirements, origin processing, and quality inspection.

6. Relevant management departments of all provinces should strengthen cooperation and form a joint force to jointly promote the standardized, standardized and intensive development of traditional Chinese medicinal materials, strengthen publicity and training according to their responsibilities, and promote the implementation of this standard. Strengthen daily supervision during implementation. If any major problems or major policy improvement suggestions are found, please report to the corresponding state management department in a timely manner.

Special announcement.

Attachment: Standard for quality management of production of Chinese medicinal materials

State Food and Drug Administration Ministry of Agriculture and Rural Affairs

State Forestry and Grass Administration State Administration of Traditional Chinese Medicine

March 1, 2022

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